skintervene Cellular Renewal Serum with Methylene Blue
Advanced Mitochondrial Skincare · Made in London

Skin that
performs
at the source.

skintervene formulates at the cellular level. Our debut serum pairs Methylene Blue, a compound with over 140 years of scientific history, with eight supporting actives for skin that looks renewed, resilient and well-hydrated.

9Actives
UKMade in London
0%Fragrance
Our Belief
"Most skincare works on the surface.
We intervene beneath it —
at the cellular machinery
that drives everything else."

Why mitochondria
change everything.

01
The Mitochondrial Decline

As skin ages, mitochondrial function declines. The organelles that power cellular energy become less efficient, and visible ageing is in part the consequence of this invisible slowdown.

02
Methylene Blue as Electron Carrier

Methylene Blue is redox-active: it cycles between oxidised and reduced states and can act as an alternative electron carrier. That is a different mechanism from conventional antioxidants, which is why it has drawn attention in skin research. Read the guide →

03
The skintervene Approach

Meaningful inclusions, not token ones. Methylene Blue, Niacinamide, Ectoin, Tremella — each chosen for what it does, not how it reads on a label, with the reasoning published in our ingredient glossary.

skintervene Cellular Renewal Serum, 40 ml

Cellular
Renewal
Serum

with Methylene Blue · 40 ml

An antioxidant-rich gel-serum built around Methylene Blue, with Niacinamide, Ectoin and Tremella for hydration, a smoother-looking texture and a more resilient-feeling barrier.

Nine carefully chosen actives
Fragrance-free · Vegan · Cruelty-free
Made in London, UK
Suitable for all skin types
£44.99 £59.99 / 40 ml · Free UK delivery
Subscribe & save 10% · cancel anytime

Nine actives.
One precise purpose.

01
Hero
Methylene Blue
Methylene Blue

Redox-active antioxidant that can act as a mitochondrial electron carrier, a different mechanism from conventional antioxidants.

02
Niacinamide
Niacinamide

Vitamin B3. Helps minimise the look of pores, balance oil and support the skin barrier. One of the best-evidenced actives in skincare.

03
Rare
Tremella Mushroom
Tremella Fuciformis Extract

The beauty mushroom. Forms a moisture-binding film with hyaluronic-acid-like hydration.

04
Ectoin
Ectoin

Natural extremolyte that holds water around skin cells, helping skin cope with pollution and environmental stress.

05
N-Acetyl Glucosamine
Acetyl Glucosamine

Supports hydration and helps even the look of tone and texture.

06
Centella Asiatica
Centella Asiatica Extract

Soothing botanical long used to calm the look of redness and support barrier comfort.

07
Green Tea Extract
Camellia Sinensis Leaf Extract

Rich in EGCG polyphenols for antioxidant defence against everyday environmental stressors.

08
Beta-Glucan
Beta-Glucan

Hydrating, soothing polysaccharide that leaves skin feeling comfortable and supple.

09
Squalane + Panthenol
Squalane · Panthenol

Skin-identical emollient and pro-vitamin B5. Locks in moisture and softens without a heavy feel.

Answered with
precision.

What is Methylene Blue and why is it in a serum?
+

Methylene Blue is a synthetic compound first made in 1876. In skincare it acts as a redox-active antioxidant that can cycle between oxidised and reduced states, a different mechanism from conventional antioxidants. Full guide →

Will it stain my skin blue?
+

No. At the concentration used, Methylene Blue is effectively colourless in the gel base and does not stain skin, fabrics or bedding.

Is it suitable for sensitive skin?
+

It is fragrance-free and designed for all skin types, with Ectoin and Centella for comfort. As with any new active, patch test first. If you take prescription medication, read our safety guide.

How long before I see a difference?
+

Skin feels more hydrated from the first use. Give texture and tone 4–6 weeks of consistent daily use, and judge the full effect at around 12 weeks.

Where is it made?
+

Made in London, in compliance with UK Cosmetics Regulations, with batch traceability on every unit.

Do you offer subscribe & save?
+

Yes. Subscribe to the Cellular Renewal Serum and save 10% on every order. Cancel anytime.

All FAQs →